Genome-Wide Analysis of DCIS

Grant number: 509050 | Funding period: 2008 - 2010

Completed

Abstract

DCIS is the most common type of noninvasive breast cancer and in some women may progress to malignant disease but little in know about how it develops. We will bring to bear our experience with cutting edge technology and access to extensive clinical resources to the analysis of a large series of pure DCIS with the aim of identifying previously unknown cancer causing genes. This data will lead to the identification of novel breast cancer genes that will assist clinical management.

Related publications (2)

Copy number analysis of ductal carcinoma in situ with and without recurrence

KL Gorringe, SM Hunter, JM Pang, K Opeskin, P Hill, SM Rowley, DYH Choong, ER Thompson, A Dobrovic, SB Fox, GB Mann, IG Campbell

2015-09-03

Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer and a frequent mammographic finding requirin..

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma

CE Johnson, KL Gorringe, ER Thompson, K Opeskin, SE Boyle, Y Wang, P Hill, GB Mann, IG Campbell

2012-06-01

Ductal carcinoma in situ (DCIS) is a nonobligate precursor to invasive ductal carcinoma (IDC). Annotation of the genetic differenc..

University of Melbourne Researchers

Ian Campbell

Bruce Mann